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The alpha 3 domain of the Qa-2 molecule is defective for CD8 binding and cytotoxic T lymphocyte activation. Itai-itai disease is thought to be the result of chronic cadmium (Cd) intoxication.

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Socioeconomic inequalities in mental well-being among Hungarian adolescents: a cross-sectional study. STATISTICAL COMPARISONS OF OUR TREATMENT RESULTS IN DIFFUSE AND CIRCUMSCRIBED ALOPECIA

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